This 33-story hotel near the Chrysler Building whisks you away from New York's constant hustle and bustle to a serene oasis where David Rockwell's minimalist décor proves instantly soothing. Clutter-free guest rooms are awash in a palette of whites, creams and earth tones, while limestone bathrooms have Frette towels and products by Frédéric Fekkai. If you have to stay in the city for more than a quick visit—or just hate to say goodbye—extended-stay suites make your time here even sweeter with luxury Poggenpohl-fitted kitchens sporting everything from Sub-Zero refrigerators to Miele dishwashers.

The Alex Hotel Amenities:

• 203 rooms. Restaurant, bar. Fitness center. Business center. Pets accepted.