A favorite since the 1920s, this idyllic country retreat sits on Boyes Hot Springs—a sacred healing ground for Native Americans—and just beyond the valley’s famous vineyards. Many of the sophisticated yet country-comfortable guest rooms have French doors that open to a private patio or balcony. Romantic suites hold fireplaces and four-poster beds. American fare has been served for more than 50 years at the Big 3 Diner, while Santé earns praise for its imaginative cuisine. Guests can relax by the pool or play a round of golf on the historic 1925 course. Inspired by the thermal mineral springs that flow underneath the inn, the spa is a destination unto itself, wowing guests with its comprehensive treatment menu.

Fairmont Sonoma Mission Inn & Spa Amenities:

• 228 rooms. Wireless Internet access. Five restaurants, three bars. Fitness classes available, spa. Whirlpool. Airport transportation available.