Well-heeled travelers kick off their shoes in the 52-story Midtown outpost of this luxe hotel chain, appropriately located steps from shopping mecca Fifth Avenue. Designed by I.M. Pei, its jaw-dropper is the 33-foot-high backlit onyx ceiling in the lobby (which led Jacqueline Kennedy Onassis to nickname it "The Cathedral.") Sweeping views of Central Park and other parts of the city are part of the allure of the guest rooms, which range in size from 500 to 800 square feet—larger than many New York City apartments—with roomy seating areas (some have furnished terraces, too). Other treats include big marble bathrooms with soaking tubs, and silk drapes that you can control bedside to open or close on those to-die-for views. Plenty of celebrities have stayed here because they can't get enough of the Four Seasons' signature top-notch service, luxurious spa and fine dining establishments, including L' Atelier de Joël Robuchon.

Four Seasons Hotel New York Amenities:

• 368 rooms. Wireless Internet access. Restaurant, bar. Fitness center. Spa. Business center. Pets accepted.