Overlooking the Chicago River, the Sheraton chain’s flagship branch touts itself as the “premier convention and business hotel in the Midwest.” In fact, its enormous size makes it seem more like a convention center than a luxury hotel. But the simply decorated cream and beige rooms with beds resting against wood-paneled walls are inviting, especially when you add in the calming views of the water. For a change of scenery, visit the surprisingly hip Chi Bar, where you can kick back in a cocoacolored leather chair with a Chicago Sunset martini and forget about the conventioneers flitting around the rest of the hotel.

Sheraton Chicago Hotel And Towers Amenities:

• 1,209 rooms. High-speed Internet access. Restaurant, bar. Fitness center. Pool. Business center. Pets accepted.